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IGF-1


About one third of the aging population secretes little or no growth hormone. If you are part of this third, the chances are that the natural growth hormone agonists will not raise the levels of IGF-1 sufficiently to have age-reversing effects. We will discuss growth hormone replacement with recombinant HGH infections. Which should also be combined with the dietary measures and Gh-releasing exercises to get the maximum muscle building benefit. HGH is the product for which there is the most experimental and clinical experience. Although work is now being done with recombinant IGF-1 and GHRH (growth hormone-releasing hormone), which may prove even more effective that growth hormone itself, this is still very preliminary.


We will tell you about the thrilling clinical studies now being performed on the growth secretagogues, which promise to transform the way in which all of us age or do not age by the turn of the century. As was mentioned before August 1996, the FDA approved HGH use for pituitary deficient adults. Before this it could only be used to promote growth in GH-deficient children.

 Human

The new indication or for SDS, or somatotrophin(growth hormone) deficiency syndrome, as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or injury. In effect, the FDA approval covers the use of HGH for anti-aging purpose since low levels of growth of IGF-1 indicate a failure of the pituitary to release adequate amounts. In addition, the signs of SDS, such as decreased physical mobility, lower energy, higher risk of cardiovascular disease, are the same as those seen in aging adults with low GH levels, The new FDA indication means that the U.S joints 12 other countries in which HGH replacement in adults has been approve, including Sweden Denmark, France, Germany, Mexico and the United Kingdom.


In 1992 for Genentech and 1994 for Lilly their exclusivity expired and other companies began scrambling to get into the act. Of making HGH. Genentech, which commands about 75 percent of the #350 million growth hormone market, waged court battles to keep the two would be competitors Novo Nor disk from Denmark and Bio technology  General Corp of Iselin, New Jersey out of the United Sates by caliming patent infringement. Novo Nordisk growth hormone has now successfully penetrated the U.S market although BTG as of this article had not. These are the five companies that now sell growth hormone (or most likely will do so in the near future) and their products, there are many companies that manufacture HGH now days.


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